Researchers at the University of Colorado Anschutz School of Dental Medicine are developing inkjet-printable polymer systems that allow precise control of mechanical properties in 3D-printed dentures. Led by Prof. Jeffrey Stansbury, the project aims to create materials where stiffness, elasticity, and other properties can be tailored for different regions of a removable prosthesis, potentially improving patient comfort and denture durability.

Antimicrobial functionality and clinical translation

Parallel research is incorporating antimicrobial and antifungal materials into the 3D-printed dentures. These materials have demonstrated significant activity against Streptococcus species and Candida. The same polymer systems and custom inkjet printer platform will support testing of these antimicrobial properties alongside future advanced materials. Prof. Stansbury noted that this approach could improve oral health for patients wearing full or partial dentures made from the new material.

From research to patient care

The dental school has established a dedicated 3D printing hub integrating materials development, clinical application, and dental education, described as the first dental school facility combining these capabilities. Students and staff can now work with the technology in patient care settings. A planned clinical trial will compare dentures printed from the new materials with conventional and milled dentures in terms of patient satisfaction and functional outcomes. A recent systematic review found that 3D-printed complete dentures show clinical outcomes broadly comparable to conventional dentures, though conventional dentures may offer stronger retention. If clinically validated, the tuneable materials could enable more sophisticated design of removable prostheses.