A systematic review and meta-analysis published in Clinical and Experimental Dental Research in April 2026 has examined how artificial intelligence affects diagnostic decision-making and patient outcomes in dentistry. While many AI systems show high technical accuracy, their real clinical value depends on whether they change how dentists make treatment decisions and whether patients benefit in the end.

How AI affects diagnostic performance and workflow

The review found that AI assistance improved clinicians' diagnostic performance and increased agreement between clinicians interpreting the same images. AI systems demonstrated high accuracy in detecting disease, identifying teeth, and mapping anatomical boundaries across different imaging contexts. The technology also accelerates diagnostic tasks, allowing dentists to complete interpretations faster without sacrificing accuracy and to locate abnormalities more precisely on dental images.

Gaps in evidence for treatment planning and patient outcomes

A major limitation emerged: the review could draw no conclusions about AI's impact on actual treatment decisions or patient outcomes. While AI appears to support treatment planning indirectly by improving image interpretation and clinician confidence in diagnosis, evidence remains sparse. The authors identified a critical research gap caused by the small number of studies, variation in clinical contexts, and the absence of patient-centred outcome measures.

Why variability in study design matters

High variability in diagnostic performance across studies reflects differences in AI models, imaging techniques, and validation methods. Many studies relied on retrospective data, and few included external validation. This raises questions about how reliably these findings translate to routine dental practice settings. The authors call for robust prospective research to confirm AI's clinical value in real-world conditions.